Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage
نویسندگان
چکیده
منابع مشابه
Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage.
Neural stem cells (NSCs) yield both neuronal and glial progeny, but their differentiation potential toward multiple region-specific neuron types remains remarkably poor. In contrast, embryonic stem cell (ESC) progeny readily yield region-specific neuronal fates in response to appropriate developmental signals. Here we demonstrate prospective and clonal isolation of neural rosette cells (termed ...
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ژورنال
عنوان ژورنال: Genes & Development
سال: 2008
ISSN: 0890-9369
DOI: 10.1101/gad.1616208